Orbimed Advisors LLC is 10% Owner at Alector, Inc. (ALEC). They have made 112 open-market trades across 51 companies since 2007, most recently 2026-09-21.
45 open-market purchases totalling $272.4M since 2007, against 67 sales. Across 37 scored buys the stock is down 2.9% at ninety days, and 4.9 points behind the S&P over the same stretch.
41 scored purchases · one row per filing · discretionary only
| 7d | 30d | 90d | |
|---|---|---|---|
| Accuracy | 54% | 38% | 38% |
| Avg Move | +2.4% | +0.3% | -2.9% |
| Alpha | +2.4% | -0.2% | -4.9% |
| Scored | 41 | 40 | 37 |
| 7d | 30d | 90d | |
|---|---|---|---|
| Accuracy | 56% | 52% | 52% |
| Avg Move | -4.7% | +0.1% | -1.3% |
| Ticker | Type | Traded | Filed | Price | Value | 7d Stock | 30d Stock | 90d Stock |
|---|---|---|---|---|---|---|---|---|
| ETRA | BUY | 2026-09-21 | 2026-09-23 | $15.00 | $20.0M | -19.5% | — | — |
| BLSM | BUY | 2026-08-10 | 2026-08-12 | $16.00 | $10.0M | -2.2% | +27.3% | — |
| BRVE | BUY | 2026-08-07 | 2026-08-11 | $18.00 | $34.9M | +6.8% | +5.9% | — |
| SCTX | BUY | 2026-07-27 | 2026-07-29 | $15.00 | $15.0M | +23.1% | +41.6% | — |
| SION | SELL · 10b5-1 | 2026-07-07 | 2026-07-09 | $44.86 | $3.9M | +9.5% | -89.5% | -88.8% |
| SION | SELL · 10b5-1 | 2026-06-30 | 2026-07-02 | $45.50 | $5.3M | +1.3% | +12.5% | -88.0% |
| ELVN | SELL | 2026-06-22 | 2026-06-24 | $45.36 | $39.0M | +6.3% | +10.5% | +0.7% |
| ELVN | SELL | 2026-06-15 | 2026-06-17 | $45.02 | $12.7M | +13.4% | +18.8% | +19.2% |
| QTTB | BUY | 2026-05-28 | 2026-06-01 | $8.00 | $15.0M | +3.7% | +2.3% | +22.4% |
| SION | SELL · 10b5-1 | 2026-05-27 | 2026-05-29 | $44.49 | $4K | -19.0% | +2.2% | -85.6% |
| SION | SELL · 10b5-1 | 2026-05-07 | 2026-05-11 | $45.62 | $13.4M | -4.5% | -22.1% | -89.7% |
| PRLD | BUY | 2026-04-21 | 2026-04-23 | $4.44 | $12.5M | -3.7% | -16.5% | -19.2% |
| SION | SELL · 10b5-1 | 2026-04-17 | 2026-04-21 | $44.67 | $2.5M | -6.3% | -0.2% | +10.1% |
| TRAW | BUY | 2026-04-16 | 2026-04-28 | $1.67 | $998K | +58.4% | +13.1% | -62.4% |
| SION | SELL · 10b5-1 | 2026-04-14 | 2026-04-16 | $44.94 | $22.9M | -14.2% | -14.9% | -3.7% |
| ACET | SELL | 2026-04-07 | 2026-04-09 | $6.45 | $675K | +17.0% | +18.6% | +33.8% |
| SION | SELL | 2025-11-24 | 2025-11-26 | $44.54 | $4.2M | -3.7% | +1.2% | -13.6% |
| ACET | BUY | 2025-10-08 | 2025-10-10 | $1.00 | $5.0M | -12.3% | -36.8% | -51.4% |
| PMVP | SELL | 2025-09-10 | 2025-09-12 | $1.80 | $900K | +21.5% | +9.1% | +3.3% |
| CRVS | SELL | 2025-06-27 | 2025-07-01 | $4.16 | $4.9M | +13.3% | +8.6% | +89.6% |
| PASG | SELL | 2025-06-24 | 2025-06-26 | $0.34 | $268K | +22.5% | -2.1% | +7.2% |
| NPCE | SELL | 2025-05-14 | 2025-05-16 | $15.84 | $4.8M | -23.3% | -35.1% | -47.2% |
| PASG | SELL | 2025-04-22 | 2025-04-24 | $0.33 | $79K | +5.4% | +11.6% | -9.9% |
| IRON | SELL | 2025-03-24 | 2025-03-26 | $54.11 | $310K | -25.9% | -14.1% | +4.0% |
| PASG | SELL | 2025-01-10 | 2025-01-14 | $0.65 | $226K | +3.7% | -11.5% | -35.2% |
Grouped by shared companies and similar filing behaviour. This is a similarity measure, not a ranking or a performance signal.
| PODD | 1,568,841 | $221.3M |
| ARPO | 5,193,946 | $171.4M |
| ALPN | 2,416,181 | $157.0M |
| STTK | 26,519,541 | $144.3M |
| MBX | 2,658,428 | $132.0M |
| PRNB | 1,070,771 | $107.1M |
| PCRX | 2,561,084 | $93.1M |
| TPTX | 1,120,730 | $85.2M |
| SRRA | 1,511,362 | $83.1M |
| NXTM | 2,690,476 | $80.7M |
| TERN | 1,326,481 | $70.3M |
| CRVS | 7,165,006 | $68.2M |
| PIRS | 4,511,130 | $61.4M |
| NPCE | 3,272,199 | $40.1M |
| BLSM | 2,714,279 | $38.1M |
| SCPH | 5,328,328 | $30.2M |
| IRON | 482,308 | $27.5M |
| ORIC | 2,212,571 | $27.3M |
| SCTX | 1,348,825 | $27.3M |
| LOGC | 3,524,997 | $24.9M |
| CCXI | 2,201,388 | $23.4M |
| PASG | 6,279,600 | $23.0M |
| JANX | 1,348,421 | $22.3M |
| ICPT | 1,122,914 | $21.3M |
| AGLE | 1,469,524 | $17.6M |
| NXTC | 2,711,013 | $16.6M |
| SIBN | 785,368 | $15.5M |
| ETRA | 1,758,279 | $15.4M |
| CMPX | 15,219,994 | $13.2M |
| INSP | 187,751 | $12.9M |
| KNTE | 4,738,453 | $12.6M |
| CNST | 317,921 | $10.8M |
| UPB | 3,894,873 | $10.7M |
| SION | 2,469,959 | $9.7M |
| BOLD | 3,696,428 | $8.6M |
| PMVP | 5,975,291 | $7.2M |
| GLTO | 179,753 | $5.2M |
| BRVE | 273,333 | $5.1M |
| QTTB | 625,000 | $4.7M |
| PRLD | 1,126,126 | $3.6M |
| ALEC | 1,906,718 | $3.5M |
| GRAY | 562,500 | $3.1M |
| THRX | 650,600 | $2.6M |
| TELA | 2,443,842 | $2.4M |
| IMA | 336,603 | $1.4M |
| DBTX | 218,568 | $1.1M |
| TCDA | 9,246,526 | $999K |
| TSBX | 2,682,599 | $952K |
| KALA | 3,447,840 | $647K |
| IKNA | 287,885 | $412K |
| GKOS | 2,291 | $378K |
| ADAP | 5,101,310 | $280K |
| RPTX | 96,911 | $257K |
| TRAW | 597,729 | $232K |
| ATHX | 1,805,100 | $184K |
| ASNS | 1,868,966 | $170K |
| AFIB | 1,677,361 | $151K |
| ACET | 32,523 | $149K |
| OTIC | 1,850,094 | $142K |
| AMRN | 11,400 | $129K |
| XTNT | 215,415 | $61K |
| SELB | 12,193 | $11K |
| ROKA | 7,718 | $5K |
| VRAY | 70,364 | $2K |
| BVIC | 3,000,000 | — |
| BIOD | 1,485,904 | — |
| AVN | 2,335,258 | — |
| PrivateUnlisted | 12,714,404 | — |
| ARMO | 3,709,356 | — |
| ANTH | 1,762,000 | — |
| RBM | 2,149,902 | — |
| ARYX | 1,340,139 | — |
| GNOM | 27,859 | — |
| Total | $4.4B |
Shares reported on the most recent Form 4, priced at the 2026-09-23 close. 9 holdings could not be priced and are excluded from the total.
Counted per filing, not per execution lot — a purchase filled in several tranches is one decision.
| Scored | 61 | 61 | 60 |