B. Lynne Parshall is Secretary at ISIS PHARMACEUTICALS INC (ISIS). They have made 30 open-market trades across 4 companies since 2006, most recently 2026-09-01.
CIK 0001073385
Unrated. We grade insiders only on stock they chose to buy on the open market. Grants, option exercises and vesting say nothing about timing, so they don't count — which is why someone can file often and still have no grade. It isn't a bad sign: unrated buys beat every graded tier below A.
1 open-market purchase totalling $3.0M since 2012, against 29 sales. Too few scored purchases to measure a record yet.
| Ticker | Shares | Value |
|---|---|---|
| RGLS | 6,943,750 | $56.7M |
| IONS | 51,344 | $2.2M |
| CYTK | 10,784 | $668K |
| "RGLS" | 6,986,900 | — |
| CDIC | 21,000 | — |
| ISIS | 11,579 | — |
| Total | $59.5M |
Shares reported on the most recent Form 4, priced at the 2026-09-01 close. 3 holdings could not be priced and are excluded from the total.
Counted per filing, not per execution lot — a purchase filled in several tranches is one decision.
| Ticker | Type | Traded | Filed | Price | Value | 7d Stock | 30d Stock | 90d Stock |
|---|---|---|---|---|---|---|---|---|
| CYTK | SELL | 2026-09-01 | 2026-09-01 | $71.48 | $357K | +0.2% | -9.4% | — |
| CYTK | SELL | 2026-06-01 | 2026-06-01 | $74.08 | $370K | -5.4% | +16.4% | -3.2% |
| IONS | SELL · 10b5-1 | 2026-04-15 | 2026-04-17 | $76.27 | $381K | -0.9% | -4.0% | -27.6% |
| CYTK | SELL | 2026-03-02 | 2026-03-02 | $61.21 | $306K | -0.5% | +10.5% | +22.2% |
| IONS | SELL · 10b5-1 | 2026-02-11 | 2026-02-13 | $82.72 | $414K | +0.4% | -9.9% | -5.8% |
| CYTK | SELL · 10b5-1 | 2025-11-19 | 2025-11-19 | $64.73 | $324K | -2.9% | -4.1% | +1.9% |
| IONS | SELL · 10b5-1 | 2025-10-15 | 2025-10-16 | $71.74 | $359K | +0.8% | +0.4% | +8.1% |
| IONS | SELL · 10b5-1 | 2025-09-02 | 2025-09-04 | $51.10 | $1.5M | +3.2% | +16.1% | +37.7% |
| IONS | SELL · 10b5-1 | 2025-08-06 | 2025-08-08 | $41.93 | $210K | +3.1% | +47.0% | +78.5% |
| CYTK | SELL · 10b5-1 | 2024-09-09 | 2024-09-09 | $54.92 | $275K | -0.8% | -2.9% | -9.9% |
| CYTK | SELL · 10b5-1 | 2024-08-26 | 2024-08-26 | $57.26 | $286K | -4.7% | -7.1% | -11.4% |
| CYTK | SELL · 10b5-1 | 2024-08-12 | 2024-08-12 | $55.20 | $276K | +2.8% | -1.8% | +7.1% |
| CYTK | SELL · 10b5-1 | 2024-07-29 | 2024-07-31 | $59.84 | $299K | -4.7% | -3.2% | -12.6% |
| CYTK | SELL · 10b5-1 | 2024-07-15 | 2024-07-16 | $55.82 | $279K | +7.3% | +2.5% | -2.1% |
| CYTK | SELL · 10b5-1 | 2024-07-01 | 2024-07-01 | $54.22 | $271K | +1.8% | +7.3% | -3.9% |
| CYTK | SELL · 10b5-1 | 2024-06-17 | 2024-06-17 | $52.55 | $263K | +2.8% | +7.7% | +7.7% |
| CYTK | SELL · 10b5-1 | 2024-06-03 | 2024-06-04 | $48.64 | $243K | +10.8% | +14.0% | +12.1% |
| IONS | SELL | 2023-12-26 | 2023-12-28 | $50.55 | $9.4M | +4.1% | +3.8% | -10.9% |
| IONS | SELL · 10b5-1 | 2023-09-26 | 2023-09-28 | $45.13 | $451K | -0.7% | -6.4% | +6.7% |
| CYTK | SELL | 2022-09-01 | 2022-09-01 | $52.79 | $3.2M | +0.1% | -5.8% | -21.7% |
| CYTK | SELL | 2021-11-05 | 2021-11-05 | $40.00 | $1.2M | -5.0% | -12.6% | -22.4% |
| CYTK | SELL | 2021-10-19 | 2021-10-20 | $35.73 | $738K | -3.2% | +15.2% | -8.7% |
| IONS | SELL | 2020-12-23 | 2020-12-28 | $60.00 | $600K | +3.7% | +0.5% | -23.7% |
| IONS | SELL | 2020-11-25 | 2020-11-30 | $50.05 | $359K | -8.2% | +13.2% | +6.9% |
| IONS | SELL | 2020-11-23 | 2020-11-25 | $50.25 | $196K | -2.1% | +17.8% | +12.1% |
Grouped by shared companies and similar filing behaviour. This is a similarity measure, not a ranking or a performance signal.