Patrick R. O'Neil is CLO & VP at IONIS PHARMACEUTICALS INC (IONS). They have made 37 open-market trades across 2 companies since 2013, most recently 2026-06-26.
CIK 0001564926
Unrated. We grade insiders only on stock they chose to buy on the open market. Grants, option exercises and vesting say nothing about timing, so they don't count — which is why someone can file often and still have no grade. It isn't a bad sign: unrated buys beat every graded tier below A.
0 open-market purchases, against 37 sales. Too few scored purchases to measure a record yet.
| Ticker | Shares | Value |
|---|---|---|
| IONS | 61,470 | $2.6M |
| ISIS | 6,259 | — |
| Total | $2.6M |
Shares reported on the most recent Form 4, priced at the 2026-06-30 close. 1 holding could not be priced and is excluded from the total.
Counted per filing, not per execution lot — a purchase filled in several tranches is one decision.
| Ticker | Type | Traded | Filed | Price | Value | 7d Stock | 30d Stock | 90d Stock |
|---|---|---|---|---|---|---|---|---|
| IONS | SELL · 10b5-1 | 2026-06-26 | 2026-06-30 | $80.00 | $246K | -28.4% | -32.7% | -42.5% |
| IONS | SELL | 2026-03-09 | 2026-03-11 | $75.25 | $764K | -4.7% | +1.2% | +0.3% |
| IONS | SELL | 2026-01-30 | 2026-02-02 | $83.53 | $516K | -1.5% | -4.3% | -9.1% |
| IONS | SELL | 2026-01-16 | 2026-01-20 | $75.84 | $697K | +7.2% | +7.9% | -2.9% |
| IONS | SELL · 10b5-1 | 2025-10-06 | 2025-10-08 | $69.65 | $1.2M | +4.8% | +4.8% | +16.1% |
| IONS | SELL · 10b5-1 | 2025-10-02 | 2025-10-02 | $67.69 | $8.8M | +4.4% | +7.8% | +15.8% |
| IONS | SELL · 10b5-1 | 2025-09-29 | 2025-10-01 | $64.62 | $3.3M | +6.6% | +12.2% | +19.3% |
| IONS | SELL · 10b5-1 | 2025-09-12 | 2025-09-16 | $64.58 | $110K | +4.3% | +18.9% | +29.8% |
| IONS | SELL · 10b5-1 | 2025-09-09 | 2025-09-11 | $64.56 | $1.4M | -2.0% | +10.6% | +23.1% |
| IONS | SELL · 10b5-1 | 2025-09-02 | 2025-09-04 | $60.03 | $10.8M | +3.2% | +16.1% | +37.7% |
| IONS | SELL · 10b5-1 | 2025-02-20 | 2025-02-24 | $32.35 | $39K | +7.2% | -1.9% | +3.8% |
| IONS | SELL · 10b5-1 | 2025-02-04 | 2025-02-06 | $31.62 | $390K | -2.3% | -1.0% | +1.6% |
| IONS | SELL | 2025-01-31 | 2025-02-03 | $32.49 | $46K | -5.0% | +5.6% | +5.3% |
| IONS | SELL | 2025-01-16 | 2025-01-17 | $32.83 | $483K | +5.4% | +1.0% | -10.2% |
| IONS | SELL | 2024-02-02 | 2024-02-02 | $49.67 | $97K | -0.7% | -9.2% | -12.8% |
| IONS | SELL | 2024-02-02 | 2024-09-04 | $49.67 | $198K | -14.7% | -20.5% | -24.9% |
| IONS | SELL | 2024-01-25 | 2024-01-29 | $51.75 | $668K | -3.4% | -10.0% | -18.8% |
| IONS | SELL | 2024-01-17 | 2024-01-18 | $50.42 | $781K | +3.2% | -11.8% | -18.7% |
| IONS | SELL | 2023-12-26 | 2023-12-28 | $51.46 | $2.1M | +4.1% | +3.8% | -10.9% |
| IONS | SELL · 10b5-1 | 2023-05-24 | 2023-05-24 | $41.70 | $127K | +5.7% | -3.3% | -4.1% |
| IONS | SELL | 2023-02-06 | 2023-02-07 | $40.86 | $157K | -5.2% | -14.6% | -13.6% |
| IONS | SELL | 2023-01-30 | 2023-02-02 | $39.57 | $356K | -4.5% | -11.7% | -15.4% |
| IONS | SELL | 2023-01-18 | 2023-01-19 | $39.49 | $619K | -1.9% | -6.0% | -9.6% |
| IONS | SELL | 2022-04-12 | 2022-04-14 | $40.06 | $544K | -2.8% | -10.7% | -8.2% |
| IONS | SELL | 2021-01-25 | 2021-01-27 | $63.50 | $338K | -0.9% | -13.1% | -28.1% |
Grouped by shared companies and similar filing behaviour. This is a similarity measure, not a ranking or a performance signal.