C. Frank Bennett is SVP & Antisense Research at ISIS PHARMACEUTICALS INC (ISIS). They have made 34 open-market trades across 2 companies since 2006, most recently 2026-07-07.
CIK 0001073387
Unrated. We grade insiders only on stock they chose to buy on the open market. Grants, option exercises and vesting say nothing about timing, so they don't count — which is why someone can file often and still have no grade. It isn't a bad sign: unrated buys beat every graded tier below A.
0 open-market purchases, against 34 sales. Too few scored purchases to measure a record yet.
| Ticker | Shares | Value |
|---|---|---|
| IONS | 75,018 | $3.2M |
| ISIS | 11,225 | — |
| Total | $3.2M |
Shares reported on the most recent Form 4, priced at the 2026-07-09 close. 1 holding could not be priced and is excluded from the total.
Counted per filing, not per execution lot — a purchase filled in several tranches is one decision.
| Ticker | Type | Traded | Filed | Price | Value | 7d Stock | 30d Stock | 90d Stock |
|---|---|---|---|---|---|---|---|---|
| IONS | SELL · 10b5-1 | 2026-07-07 | 2026-07-09 | $84.95 | $1.7M | -17.1% | -11.7% | -31.4% |
| IONS | SELL | 2026-03-03 | 2026-03-05 | $79.23 | $6.7M | -2.2% | +0.5% | -0.2% |
| IONS | SELL | 2026-02-02 | 2026-02-04 | $82.93 | $7.1M | -3.7% | -12.4% | -11.0% |
| IONS | SELL | 2026-01-30 | 2026-02-02 | $82.95 | $488K | -1.5% | -4.3% | -9.1% |
| IONS | SELL | 2026-01-16 | 2026-01-20 | $75.15 | $675K | +7.2% | +7.9% | -2.9% |
| IONS | SELL · 10b5-1 | 2025-09-05 | 2025-09-09 | $59.60 | $358K | -5.1% | +9.3% | +26.8% |
| IONS | SELL · 10b5-1 | 2025-09-02 | 2025-09-04 | $59.83 | $4.4M | +3.2% | +16.1% | +37.7% |
| IONS | SELL · 10b5-1 | 2025-08-18 | 2025-08-20 | $43.98 | $880K | +35.0% | +43.2% | +74.9% |
| IONS | SELL | 2025-01-31 | 2025-02-03 | $32.46 | $43K | -5.0% | +5.6% | +5.3% |
| IONS | SELL | 2025-01-16 | 2025-01-17 | $32.90 | $444K | +5.4% | +1.0% | -10.2% |
| IONS | SELL | 2024-02-02 | 2024-02-02 | $49.52 | $92K | -0.7% | -9.2% | -12.8% |
| IONS | SELL | 2024-02-02 | 2024-09-04 | $49.52 | $187K | -14.7% | -20.5% | -24.9% |
| IONS | SELL | 2024-01-17 | 2024-01-18 | $50.42 | $680K | +3.2% | -11.8% | -18.7% |
| IONS | SELL | 2023-12-20 | 2023-12-22 | $49.35 | $1.9M | -1.8% | -1.2% | -17.2% |
| IONS | SELL | 2023-12-14 | 2023-12-18 | $49.58 | $2.2M | -0.6% | +0.8% | -17.4% |
| IONS | SELL · 10b5-1 | 2023-09-28 | 2023-09-29 | $46.50 | $207K | +3.7% | -2.7% | +11.7% |
| IONS | SELL | 2023-02-06 | 2023-02-07 | $40.57 | $147K | -5.2% | -14.6% | -13.6% |
| IONS | SELL | 2023-01-18 | 2023-01-19 | $38.89 | $543K | -1.9% | -6.0% | -9.6% |
| IONS | SELL | 2020-12-04 | 2020-12-08 | $51.04 | $811K | +11.1% | +20.9% | +4.6% |
| IONS | SELL | 2020-12-02 | 2020-12-04 | $51.32 | $724K | -2.8% | +10.8% | +0.0% |
| IONS | SELL | 2020-11-03 | 2020-11-05 | $46.77 | $702K | +7.6% | +3.1% | +25.5% |
| IONS | SELL | 2020-06-25 | 2020-06-29 | $59.77 | $897K | +5.1% | -0.5% | -17.0% |
| IONS | SELL | 2019-02-01 | 2019-02-05 | $58.29 | $1.1M | +1.2% | +19.7% | +24.8% |
| IONS | SELL | 2018-11-01 | 2018-11-01 | $49.54 | $619K | -0.1% | +14.9% | +8.0% |
| IONS | SELL | 2018-08-08 | 2018-08-09 | $45.00 | $563K | +11.5% | -6.7% | +13.7% |
Grouped by shared companies and similar filing behaviour. This is a similarity measure, not a ranking or a performance signal.