Joseph Loscalzo is Director at IONIS PHARMACEUTICALS INC (IONS). They have made 2 open-market trades across 1 company since 2024, most recently 2026-05-04.
CIK 0001276128
Unrated. We grade insiders only on stock they chose to buy on the open market. Grants, option exercises and vesting say nothing about timing, so they don't count — which is why someone can file often and still have no grade. It isn't a bad sign: unrated buys beat every graded tier below A.
0 open-market purchases, against 2 sales. Too few scored purchases to measure a record yet.
| Ticker | Shares | Value |
|---|---|---|
| IONS | 36,330 | $1.6M |
| CYPH | 74,700 | $192K |
| ISIS | 1,605 | — |
| Total | $1.8M |
Shares reported on the most recent Form 4, priced at the 2026-05-06 close. 1 holding could not be priced and is excluded from the total.
Counted per filing, not per execution lot — a purchase filled in several tranches is one decision.
| Ticker | Type | Traded | Filed | Price | Value | 7d Stock | 30d Stock | 90d Stock |
|---|---|---|---|---|---|---|---|---|
| IONS | SELL · 10b5-1 | 2026-05-04 | 2026-05-06 | $75.06 | $5.8M | -5.1% | -2.7% | -28.0% |
| IONS | SELL | 2026-03-03 | 2026-03-05 | $80.26 | $83K | -2.2% | +0.5% | -0.2% |
| IONS | SELL · 10b5-1 | 2025-10-31 | 2025-11-03 | $75.10 | $1.2M | -3.5% | +13.0% | +14.7% |
| IONS | SELL | 2025-09-03 | 2025-09-04 | $60.15 | $962K | +3.2% | +16.1% | +37.7% |
| IONS | SELL · 10b5-1 | 2024-11-12 | 2024-11-14 | $37.86 | $1.0M | -5.0% | +2.3% | -17.2% |
Grouped by shared companies and similar filing behaviour. This is a similarity measure, not a ranking or a performance signal.