John J. Alam is EVP & Med. Dev. Group & CMO at VERTEX PHARMACEUTICALS INC / MA (VRTX). They have made 3 open-market trades across 1 company since 2006, most recently 2025-11-17.
CIK 0001197014
Unrated. We grade insiders only on stock they chose to buy on the open market. Grants, option exercises and vesting say nothing about timing, so they don't count — which is why someone can file often and still have no grade. It isn't a bad sign: unrated buys beat every graded tier below A.
3 open-market purchases totalling $465K since 2025, never a sale. Too few scored purchases to measure a record yet.
| Ticker | Shares | Value |
|---|---|---|
| VRTX | 141,045 | $70.5M |
| CRVO | 12,500 | $28K |
| Total | $70.5M |
Shares reported on the most recent Form 4, priced at the 2025-11-19 close.
Counted per filing, not per execution lot — a purchase filled in several tranches is one decision.
| Ticker | Type | Traded | Filed | Price | Value | 7d Stock | 30d Stock | 90d Stock |
|---|---|---|---|---|---|---|---|---|
| CRVO | BUY | 2025-11-17 | 2025-11-19 | $8.46 | $365K | -5.0% | -12.1% | -47.5% |
| CRVO | BUY | 2025-11-13 | 2025-11-17 | $7.53 | $59K | +22.6% | -1.5% | -44.0% |
| CRVO | BUY | 2025-11-12 | 2025-11-13 | $7.35 | $41K | +34.8% | +16.9% | -32.8% |
| VRTX | SELL · 10b5-1 | 2008-10-01 | 2008-10-02 | $32.65 | $139K | -21.7% | -0.1% | -0.1% |
| VRTX | SELL · 10b5-1 | 2008-09-10 | 2008-09-11 | $26.23 | $173K | -21.7% | -0.1% | -0.1% |
| VRTX | SELL · 10b5-1 | 2008-09-03 | 2008-09-04 | $25.86 | $171K | -21.7% | -0.1% | -0.1% |
| VRTX | SELL · 10b5-1 | 2008-08-27 | 2008-08-28 | $27.02 | $179K | -21.7% | -0.1% | -0.1% |
| VRTX | SELL · 10b5-1 | 2008-08-20 | 2008-08-21 | $27.57 | $182K | -21.7% | -0.1% | -0.1% |
| VRTX | SELL · 10b5-1 | 2008-05-20 | 2008-05-22 | $27.62 | $22K | -21.7% | -0.1% | -0.1% |
| VRTX | SELL · 10b5-1 | 2007-12-11 | 2007-12-12 | $25.62 | $12K | -21.7% | -0.1% | -0.1% |
| VRTX | SELL · 10b5-1 | 2007-11-16 | 2007-11-19 | $25.82 | $26 | -21.7% | -0.1% | -0.1% |
| VRTX | SELL · 10b5-1 | 2007-08-06 | 2007-08-08 | $35.00 | $1.1M | -21.7% | -0.1% | -0.1% |
| VRTX | SELL · 10b5-1 | 2007-05-17 | 2007-05-21 | $31.95 | $25K | -21.7% | -0.1% | -0.1% |
| VRTX | SELL · 10b5-1 | 2007-05-07 | 2007-05-08 | $30.59 | $994K | -21.7% | -0.1% | -0.1% |
| VRTX | SELL · 10b5-1 | 2007-01-31 | 2007-02-01 | $35.46 | $53K | -21.7% | -0.1% | -0.1% |
| VRTX | SELL · 10b5-1 | 2007-01-24 | 2007-01-26 | $36.20 | $54K | -21.7% | -0.1% | -0.1% |
| VRTX | SELL · 10b5-1 | 2007-01-17 | 2007-01-18 | $38.29 | $57K | -21.7% | -0.1% | -0.1% |
| VRTX | SELL · 10b5-1 | 2007-01-10 | 2007-01-11 | $35.00 | $53K | -21.7% | -0.1% | -0.1% |
| VRTX | SELL · 10b5-1 | 2007-01-03 | 2007-01-04 | $37.28 | $56K | -21.7% | -0.1% | -0.1% |
| VRTX | SELL · 10b5-1 | 2006-12-27 | 2006-12-28 | $37.56 | $56K | -21.7% | -0.1% | -0.1% |
| VRTX | SELL · 10b5-1 | 2006-12-20 | 2006-12-21 | $37.78 | $57K | -21.7% | -0.1% | -0.1% |
| VRTX | SELL · 10b5-1 | 2006-12-13 | 2006-12-15 | $38.62 | $76K | -21.7% | -0.1% | -0.1% |
| VRTX | SELL · 10b5-1 | 2006-12-06 | 2006-12-07 | $44.69 | $67K | -21.7% | -0.1% | -0.1% |
| VRTX | SELL · 10b5-1 | 2006-11-29 | 2006-11-30 | $44.21 | $66K | -21.7% | -0.1% | -0.1% |
| VRTX | SELL · 10b5-1 | 2006-11-22 | 2006-11-27 | $44.36 | $67K | -21.7% | -0.1% | -0.1% |
Grouped by shared companies and similar filing behaviour. This is a similarity measure, not a ranking or a performance signal.