Sharon Shacham is President & CSO at Karyopharm Therapeutics Inc. (KPTI). They have made 50 open-market trades across 1 company since 2014, most recently 2026-05-18.
CIK 0001588438
Unrated. We grade insiders only on stock they chose to buy on the open market. Grants, option exercises and vesting say nothing about timing, so they don't count — which is why someone can file often and still have no grade. It isn't a bad sign: unrated buys beat every graded tier below A.
0 open-market purchases, against 50 sales. Too few scored purchases to measure a record yet.
| Ticker | Type | Traded | Filed | Price | Value | 7d Stock | 30d Stock | 90d Stock |
|---|---|---|---|---|---|---|---|---|
| KPTI | SELL | 2022-02-28 | 2022-03-02 | $10.24 | $128K | -3.8% | +27.3% | -0.8% |
| KPTI | SELL | 2022-02-17 | 2022-02-22 | $12.12 | $440K | -43.1% | -25.2% | -43.9% |
| KPTI | SELL | 2022-02-07 | 2022-02-09 | $9.86 | $266K | +19.2% | -26.7% | -32.8% |
| KPTI | SELL · 10b5-1 | 2021-03-18 | 2021-03-23 | $12.39 | $50K | +0.1% | -13.3% | -4.8% |
| KPTI | SELL | 2021-02-18 | 2021-02-22 | $14.83 | $282K | -21.1% | -29.9% | -36.9% |
| KPTI | SELL | 2021-02-11 | 2021-02-17 | $15.52 | $411K | -8.0% | -19.3% | -37.5% |
| KPTI | SELL | 2020-10-12 | 2020-10-14 | $14.89 | $112K | +1.0% | -2.1% | -2.0% |
| KPTI | SELL · 10b5-1 | 2020-08-17 | 2020-08-18 | $15.00 | $22K | -2.8% | +5.7% | +6.5% |
| KPTI | SELL | 2020-07-15 | 2020-07-17 | $19.43 | $146K | -12.1% | -19.6% | -17.3% |
| KPTI | SELL | 2020-07-09 | 2020-07-13 | $19.27 | $289K | +0.2% | -20.1% | -18.7% |
| KPTI | SELL | 2020-06-22 | 2020-06-24 | $20.00 | $150K | +4.1% | -2.3% | -11.4% |
| KPTI | SELL | 2020-06-15 | 2020-06-17 | $16.38 | $240K | -2.6% | +2.5% | -14.0% |
| KPTI | SELL | 2020-06-09 | 2020-06-11 | $18.32 | $275K | +15.9% | +4.8% | -10.2% |
| KPTI | SELL | 2020-05-15 | 2020-05-19 | $19.33 | $290K | -4.8% | +3.6% | -15.2% |
| KPTI | SELL | 2020-05-07 | 2020-05-11 | $19.63 | $147K | -7.8% | -15.2% | -26.6% |
| KPTI | SELL | 2020-04-08 | 2020-04-10 | $19.63 | $393K | +20.9% | +0.1% | -8.3% |
| KPTI | SELL | 2020-03-09 | 2020-03-11 | $22.30 | $623K | -5.9% | +3.9% | -7.6% |
| KPTI | SELL | 2020-02-19 | 2020-02-21 | $16.48 | $291K | +70.1% | +16.9% | +22.2% |
| KPTI | SELL | 2020-02-10 | 2020-02-12 | $17.18 | $344K | -11.0% | +13.6% | +18.4% |
| KPTI | SELL | 2020-01-08 | 2020-01-10 | $18.88 | $378K | -6.1% | -4.1% | +11.2% |
| KPTI | SELL | 2019-12-09 | 2019-12-11 | $16.51 | $330K | +14.3% | +9.5% | +37.7% |
| KPTI | SELL | 2019-11-08 | 2019-11-12 | $14.70 | $294K | +6.0% | +10.8% | +15.4% |
| KPTI | SELL | 2019-11-01 | 2019-11-05 | $12.00 | $120K | +9.5% | +22.5% | +17.5% |
| KPTI | SELL | 2019-09-16 | 2019-09-17 | $12.00 | $120K | -15.9% | -7.0% | +45.5% |
| KPTI | SELL | 2019-01-07 | 2019-01-09 | $10.23 | $128K | -10.8% | -14.3% | -50.1% |
Grouped by shared companies and similar filing behaviour. This is a similarity measure, not a ranking or a performance signal.